The lymphatic system is composed of a network of vessels, similar to blood vessels, that branch throughout the body. Bean-shaped organs called lymph nodes are located along this network of vessels. The lymph system carries a clear fluid called lymph, which contains white blood cells and other infection fighting substances necessary for a healthy immune system.
If you’ve been diagnosed with breast cancer, one of the first steps in planning your appropriate treatment regimen is staging the disease. One method of finding out the stage, or extent of breast cancer is removing some lymph nodes and examining the tissue under a microscope to check for cancerous cells. Clusters of lymph nodes are located in the underarm area and in the chest wall. Removing lymph nodes involves severing lymphatic vessels, which can disrupt the flow of lymph. Breast cancer treatments like radiation therapy also damage the lymphatic system, and the tumor itself can block the flow of lymph. All of these can lead to a condition called lymphedema.
When a breast cancer patient has lymphedema, the arm on the affected side swells as lymph fluid accumulates faster than the vessels can drain it. The arm can become red and tender, and the area is increasingly susceptible to infection. Over time, the lymphatic vessels become stretched out from the burden of carrying excess fluid, and the vessels lose their elasticity and ability to function effectively. In severe cases of lymphedema, the cancer patient’s arm stiffens and the patient loses mobility.
Although doctors don’t consider lymphedema to be a life-threatening condition, the swelling and pain that accompany lymphedema reduce the quality of life for breast cancer patients. Doctors treat advanced lymphedema as a chronic condition that patients must manage for life, rather than considering a cure. You must take steps to prevent lymphedema from occurring, and if you see early signs of lymphedema, you must treat it promptly to prevent this condition from progressing to the advanced, chronic form.
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Source:
National Cancer Institute's PDQ Summary